 | "ACTC1 Variants Result in Isolated and Syndromic Cardiac Phenotypes." Zarate YA, Abdelmoti L, Oh S, White A, Starks C, Au MG, Chen J, Weaver NK, Korotkov KV, Galperin E. Clin Genet. 2025 May 27. doi: 10.1111/cge.14775. [ PubMed Link ] | [ Full text ] |
 | "Signaling scaffold Shoc2 regulates lymphangiogenesis by suppressing mTORC1-mediated IFN responses." Wilson P, Vishwakarma V, Norcross R, Khaire K, Pham VN, Weinstein BM, Jung HM, Galperin E. bioRxiv [Preprint]. 2025 Apr 28:2025.03.26.645567. doi: 10.1101/2025.03.26.645567 [ PubMed Link ] | [ Full text ] |
 | "The expression of congenital Shoc2 variants induces AKT-dependent crosstalk activation of the ERK1/2 pathway." Wilson PG, Abdelmoti L, Gao T, Galperin E. Hum Mol Genet. 2024 Sep 3;33(18):1592-1604. doi: 10.1093/hmg/ddae100 [ PubMed Link ] | [ Full text ] |
 | "The expression of congenital Shoc2 variants induces AKT-dependent feedback activation of the ERK1/2 pathway." Wilson PG, Abdelmoti L, Gao T, Galperin E. bioRxiv [Preprint]. 2023 Dec 24:2023.12.23.573219. doi: 10.1101/2023.12.23.573219. Update in: Hum Mol Genet. 2024 Sep 3;33(18):1592-1604. doi: 10.1093/hmg/ddae100. [ PubMed Link ] | [ Full text ] |
 | "Shoc2 controls ERK1/2-driven neural crest development by balancing components of the extracellular matrix." Norcross RG, Abdelmoti L, Rouchka EC, Andreeva K, Tussey O, Landestoy D, Galperin E. Dev Biol. 2022 Dec;492:156-171. doi: 10.1016/j.ydbio.2022.10.010. Epub 2022 Oct 18. [ PubMed Link ] | [ Full text ] |
 | "The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery." Kontaridis MI, Roberts AE, Schill L, Schoyer L, Stronach B, Andelfinger G, Aoki Y, Axelrad ME, Bakker A, Bennett AM, Broniscer A, Castel P, Chang CA, Cyganek L, Das TK, den Hertog J, Galperin E, Garg S, Gelb BD, Gordon K, Green T, Gripp KW, Itkin M, Kiuru M, Korf BR, Livingstone JR, López-Juárez A, Magoulas PL, Mansour S, Milner T, Parker E, Pierpont EI, Plouffe K, Rauen KA, Shankar SP, Smith SB, Stevenson DA, Tartaglia M, Van R, Wagner ME, Ware SM, Zenker M. Am J Med Genet A. 2022 Jun;188(6):1915-1927. doi: 10.1002/ajmg.a.62716. Epub 2022 Mar 9. [ PubMed Link ] | [ Full text ] |
 | "The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair." Wilson P, Abdelmoti L, Norcross R, Jang ER, Palayam M, Galperin E. J Cell Sci. 2021 Nov 1;134(21):jcs258922. doi: 10.1242/jcs.258922. Epub 2021 Nov 5. [ PubMed Link ] | [ Full text ] |
 | "The leucine-rich repeat signaling scaffolds Shoc2 and Erbin: cellular mechanism and role in disease." Jang H, Stevens P, Gao T, Galperin E. FEBS J. 2021 Feb;288(3):721-739. doi: 10.1111/febs.15450. Epub 2020 Jul 6. [ PubMed Link ] | [ Full text ] |
 | "Single-domain antibodies for functional targeting of the signaling scaffold Shoc2." Jang H, Wilson PG, Sau M, Chawla U, Rodgers DW, Galperin E. Mol Immunol. 2020 Feb;118:110-116. doi: 10.1016/j.molimm.2019.12.010. Epub 2019 Dec 20. [ PubMed Link ] | [ Full text ] |
 | "VCP/p97 controls signals of the ERK1/2 pathway transmitted via the Shoc2 scaffolding complex: novel insights into IBMPFD pathology." Jang H, Jang ER, Wilson PG, Anderson D, Galperin E. Mol Biol Cell. 2019 Jul 1;30(14):1655-1663. doi: 10.1091/mbc.E19-03-0144. Epub 2019 May 15. [ PubMed Link ] | [ Full text ] |
 | "Hematopoietic and neural crest defects in zebrafish shoc2 mutants: a novel vertebrate model for Noonan-like syndrome." Jang H, Oakley E, Forbes-Osborne M, Kesler MV, Norcross R, Morris AC, Galperin E. Hum Mol Genet. 2019 Feb 1;28(3):501-514. doi: 10.1093/hmg/ddy366. [ PubMed Link ] | [ Full text ] |
 | "Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes." Song, E.S.;Jang, H.;Guo, H.F.;Juliano, M.A.;Juliano, L.;Morris, A.J.;Galperin, E.;Rodgers, D.W.;Hersh, L.B. Proceedings of the National Academy of Sciences of the United States of America 114, 14 (2017): E2826-E2835. [ PubMed Link ] | [ Full text ] |
 | "Shoc2-tranduced ERK1/2 motility signals--Novel insights from functional genomics." Jeoung, M.;Jang, E.R.;Liu, J.;Wang, C.;Rouchka, E.C.;Li, X.;Galperin, E. Cellular signalling 28, 5 (2016): 448-59. [ PubMed Link ] | [ Full text ] |
| "Data set for transcriptional response to depletion of the Shoc2 scaffolding protein." Rouchka, E.C.;Jeoung, M.;Jang, E.R.;Liu, J.;Wang, C.;Li, X.;Galperin, E. Data in brief 7, (2016): 770-8. [ PubMed Link ] | [ Full text ] |
 | "The function of Shoc2: A scaffold and beyond." Jang, E.R.;Galperin, E. Communicative & integrative biology 9, 4 (2016): e1188241. [ PubMed Link ] | [ Full text ] |
 | "Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5." Jang, E.R.;Jang, H.;Shi, P.;Popa, G.;Jeoung, M.;Galperin, E. Journal of cell science 128, 23 (2015): 4428-41. [ PubMed Link ] | [ Full text ] |
 | "HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold." Jang, E.R.;Shi, P.;Bryant, J.;Chen, J.;Dukhande, V.;Gentry, M.S.;Jang, H.;Jeoung, M.;Galperin, E. Molecular and cellular biology 34, 19 (2014): 3579-93. [ PubMed Link ] | [ Full text ] |
 | "A Novel SHOC2 Variant in Rasopathy." Hannig, V.;Jeoung, M.;Jang, E.R.;Phillips JA, 3rd;Galperin, E. Human mutation 35, 11 (2014): 1290-4. [ PubMed Link ] | [ Full text ] |
| "Dynamic changes in dopamine neuron function after DNSP-11 treatment: effects in vivo and increased ERK 1/2 phosphorylation in vitro." Fuqua, J.L.;Littrell, O.M.;Lundblad, M.;Turchan-Cholewo, J.;Abdelmoti, L.G.;Galperin, E.;Bradley, L.H.;Cass, W.A.;Gash, D.M.;Gerhardt, G.A. Peptides 54, (2014): 1-8. [ PubMed Link ] | [ Full text ] |
| "Visualizing of signaling proteins on endosomes utilizing knockdown and reconstitution approach." Jeoung, M.;Galperin, E. Methods in enzymology 534, (2014): 47-63. [ PubMed Link ] | [ Full text ] |
 | "Functional Integration of the Conserved Domains of Shoc2 Scaffold." Jeoung, M.;Abdelmoti, L.;Jang, E.R.;Vander Kooi, C.W.;Galperin, E. PloS one 8, 6 (2013): e66067. [ PubMed Link ] | [ Full text ] |
 | "Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells." Galperin, E.;Abdelmoti, L.;Sorkin, A. PloS one 7, 5 (2012): e36469. [ PubMed Link ] | [ Full text ] |
 | "Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis." Galperin, E.;Sorkin, A. Traffic (Copenhagen, Denmark) 9, 10 (2008): 1776-90. [ PubMed Link ] | [ Full text ] |
| "Recycling to the plasma membrane is delayed in EHD1 knockout mice." Rapaport, D.;Auerbach, W.;Naslavsky, N.;Pasmanik-Chor, M.;Galperin, E.;Fein, A.;Caplan, S.;Joyner, A.L.;Horowitz, M. Traffic (Copenhagen, Denmark) 7, 1 (2006): 52-60. [ PubMed Link ] | [ Full text ] |
 | "Visualization of Rab5 activity in living cells using FRET microscopy." Galperin, E.;Sorkin, A. Methods in enzymology 403, (2005): 119-34. [ PubMed Link ] | [ Full text ] |
 | "Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells." Galperin, E.;Verkhusha, V.V.;Sorkin, A. Nature methods 1, 3 (2004): 209-17. [ PubMed Link ] | [ Full text ] |
| "Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy." Sorkina, T.;Doolen, S.;Galperin, E.;Zahniser, N.R.;Sorkin, A. The Journal of biological chemistry 278, 30 (2003): 28274-83. [ PubMed Link ] | [ Full text ] |
| "Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis." Galperin, E.;Sorkin, A. Journal of cell science 116, Pt 23 (2003): 4799-810. [ PubMed Link ] | [ Full text ] |
| "EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1." Galperin, E.;Benjamin, S.;Rapaport, D.;Rotem-Yehudar, R.;Tolchinsky, S.;Horowitz, M. Traffic (Copenhagen, Denmark) 3, 8 (2002): 575-89. [ PubMed Link ] | [ Full text ] |
| "Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29." Rotem-Yehudar, R.;Galperin, E.;Horowitz, M. The Journal of biological chemistry 276, 35 (2001): 33054-60. [ PubMed Link ] | [ Full text ] |
| "Evaluation and molecular characterization of EHD1, a candidate gene for Bardet-Biedl syndrome 1 (BBS1)." Haider, N.B.;Searby, C.;Galperin, E.;Mintz, L.;Horowitz, M.;Stone, E.M.;Sheffield, V.C. Gene 240, 1 (1999): 227-32. [ PubMed Link ] | [ Full text ] |
| "EHD1--an EH-domain-containing protein with a specific expression pattern." Mintz, L.;Galperin, E.;Pasmanik-Chor, M.;Tulzinsky, S.;Bromberg, Y.;Kozak, C.A.;Joyner, A.;Fein, A.;Horowitz, M. Genomics 59, 1 (1999): 66-76. [ PubMed Link ] | [ Full text ] |
| "Identification of factors regulating the expression of the human glucocerebrosidase gene." Moran, D.;Galperin, E.;Horowitz, M. Gene 194, 2 (1997): 201-13. [ PubMed Link ] | [ Full text ] |
|
