PubMed Publications:

"Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes." Song, E.S.;Jang, H.;Guo, H.F.;Juliano, M.A.;Juliano, L.;Morris, A.J.;Galperin, E.;Rodgers, D.W.;Hersh, L.B. Proceedings of the National Academy of Sciences of the United States of America 114, 14 (2017): E2826-E2835. [ PubMed Link ] | [ Full text ]
"Shoc2-tranduced ERK1/2 motility signals--Novel insights from functional genomics." Jeoung, M.;Jang, E.R.;Liu, J.;Wang, C.;Rouchka, E.C.;Li, X.;Galperin, E. Cellular signalling 28, 5 (2016): 448-59. [ PubMed Link ] | [ Full text ]
"Data set for transcriptional response to depletion of the Shoc2 scaffolding protein." Rouchka, E.C.;Jeoung, M.;Jang, E.R.;Liu, J.;Wang, C.;Li, X.;Galperin, E. Data in brief 7, (2016): 770-8. [ PubMed Link ] | [ Full text ]
"The function of Shoc2: A scaffold and beyond." Jang, E.R.;Galperin, E. Communicative & integrative biology 9, 4 (2016): e1188241. [ PubMed Link ] | [ Full text ]
"Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5." Jang, E.R.;Jang, H.;Shi, P.;Popa, G.;Jeoung, M.;Galperin, E. Journal of cell science 128, 23 (2015): 4428-41. [ PubMed Link ] | [ Full text ]
"HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold." Jang, E.R.;Shi, P.;Bryant, J.;Chen, J.;Dukhande, V.;Gentry, M.S.;Jang, H.;Jeoung, M.;Galperin, E. Molecular and cellular biology 34, 19 (2014): 3579-93. [ PubMed Link ] | [ Full text ]
"A Novel SHOC2 Variant in Rasopathy." Hannig, V.;Jeoung, M.;Jang, E.R.;Phillips JA, 3rd;Galperin, E. Human mutation 35, 11 (2014): 1290-4. [ PubMed Link ] | [ Full text ]
"Dynamic changes in dopamine neuron function after DNSP-11 treatment: effects in vivo and increased ERK 1/2 phosphorylation in vitro." Fuqua, J.L.;Littrell, O.M.;Lundblad, M.;Turchan-Cholewo, J.;Abdelmoti, L.G.;Galperin, E.;Bradley, L.H.;Cass, W.A.;Gash, D.M.;Gerhardt, G.A. Peptides 54, (2014): 1-8. [ PubMed Link ] | [ Full text ]
"Visualizing of signaling proteins on endosomes utilizing knockdown and reconstitution approach." Jeoung, M.;Galperin, E. Methods in enzymology 534, (2014): 47-63. [ PubMed Link ] | [ Full text ]
"Functional Integration of the Conserved Domains of Shoc2 Scaffold." Jeoung, M.;Abdelmoti, L.;Jang, E.R.;Vander Kooi, C.W.;Galperin, E. PloS one 8, 6 (2013): e66067. [ PubMed Link ] | [ Full text ]
"Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells." Galperin, E.;Abdelmoti, L.;Sorkin, A. PloS one 7, 5 (2012): e36469. [ PubMed Link ] | [ Full text ]
"Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis." Galperin, E.;Sorkin, A. Traffic (Copenhagen, Denmark) 9, 10 (2008): 1776-90. [ PubMed Link ] | [ Full text ]
"Recycling to the plasma membrane is delayed in EHD1 knockout mice." Rapaport, D.;Auerbach, W.;Naslavsky, N.;Pasmanik-Chor, M.;Galperin, E.;Fein, A.;Caplan, S.;Joyner, A.L.;Horowitz, M. Traffic (Copenhagen, Denmark) 7, 1 (2006): 52-60. [ PubMed Link ] | [ Full text ]
"Visualization of Rab5 activity in living cells using FRET microscopy." Galperin, E.;Sorkin, A. Methods in enzymology 403, (2005): 119-34. [ PubMed Link ] | [ Full text ]
"Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells." Galperin, E.;Verkhusha, V.V.;Sorkin, A. Nature methods 1, 3 (2004): 209-17. [ PubMed Link ] | [ Full text ]
"Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy." Sorkina, T.;Doolen, S.;Galperin, E.;Zahniser, N.R.;Sorkin, A. The Journal of biological chemistry 278, 30 (2003): 28274-83. [ PubMed Link ] | [ Full text ]
"Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis." Galperin, E.;Sorkin, A. Journal of cell science 116, Pt 23 (2003): 4799-810. [ PubMed Link ] | [ Full text ]
"EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1." Galperin, E.;Benjamin, S.;Rapaport, D.;Rotem-Yehudar, R.;Tolchinsky, S.;Horowitz, M. Traffic (Copenhagen, Denmark) 3, 8 (2002): 575-89. [ PubMed Link ] | [ Full text ]
"Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29." Rotem-Yehudar, R.;Galperin, E.;Horowitz, M. The Journal of biological chemistry 276, 35 (2001): 33054-60. [ PubMed Link ] | [ Full text ]
"Evaluation and molecular characterization of EHD1, a candidate gene for Bardet-Biedl syndrome 1 (BBS1)." Haider, N.B.;Searby, C.;Galperin, E.;Mintz, L.;Horowitz, M.;Stone, E.M.;Sheffield, V.C. Gene 240, 1 (1999): 227-32. [ PubMed Link ] | [ Full text ]
"EHD1--an EH-domain-containing protein with a specific expression pattern." Mintz, L.;Galperin, E.;Pasmanik-Chor, M.;Tulzinsky, S.;Bromberg, Y.;Kozak, C.A.;Joyner, A.;Fein, A.;Horowitz, M. Genomics 59, 1 (1999): 66-76. [ PubMed Link ] | [ Full text ]
"Identification of factors regulating the expression of the human glucocerebrosidase gene." Moran, D.;Galperin, E.;Horowitz, M. Gene 194, 2 (1997): 201-13. [ PubMed Link ] | [ Full text ]